the effect of nicotine was already mentioned in this edition
    of the book , with years and years of thorough experiments
    and investigations .
    cigarette smoking was a concern in that era , while during my time
    now in 2015 , ' vape ' / e-cigarette with unmonitored
    nicotine contents became a phenomenon , with people smoking it
    justifying it as safer than traditional tobacco cigarette.
    for now i don't have a word whether e-cig is truly safe of not ,
    but I assume these e-cig smokers nowdays are voluntarily
    becoming a ' lab-rat ' for the long term studies of the effect
    of e-cig , and studies about it will be published in the
    future edition of the book.




    i got this 1987 Eleventh Edition Harrison's Principles of Internal Medicine
    from a pawn shop in Alor Setar , Kedah for only
    RM35 for a complete set of volume 1 and volume 2.